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You are here: Home / Ultimate Skin Infection Defense – MRSA Included / Clinical Studies on Skin Defense

Clinical Studies on Skin Defense

(There are clinical studies topically related to our research here.  We prefer to base our nutritional products on clinical studies more than testimonies.  Some studies are listed at the end of particular articles. More can be found under the general topics of Monolaurin, Lactoferrin, Essential Oils, etc.)

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   “All these papers confirm what initially was truly surprising: that on human skin, monolaurin is an antiseptic with broad-spectrum effects. A second surprise was its novel mechanism of action that sets it apart from other currently used antibiotics (Carpo et al, 2007).”        Vermén M. Verallo-Rowell, MD, FABD, FABDP, FPDS Clinical Professor in Dermatology, Skin and Cancer Foundation, Inc.  Section Head, Dermatopathology, Makati Medical Center

Abraham ERL, Verallo-Rowell VM, Baello BQ. 2000. Testing of (monolaurin) versus isopropyl alcohol for antisepsis of cutaneous hand microbes to prevent infection. Philipp J Microbiol Infect Dis 29:128-135.

Abraham ERL, Verallo-Rowell VM. 2001. Safety and efficacy of monolaurin, a coconut extract vs isopropyl alcohol in rinse-free hand antiseptic gels on healthcare personnel’s hands and microbial isolates. Philipp Dermatol Soc J 10: 90-99.

Beatriz G. Carpo, Vermen M. Verallo-Rowell, Jon Kabara. (2007) Novel antibacterial activity of monolaurin compared with conventional antibiotics against organisms from skin infections: an in vitro study. Journal of Drugs in Dermatology.

Bruzzese N, Sica G, Iacopino F, et al. Growth inhibition of fibroblasts from nasal polyps and normal skin by lysine acetylsalicylate. Allergy. 1998;53:431-434.

Carpo T, Verallo-Rowell VM, Kabara J. 2007. Novel antibacterial activity of monolaurin compared with conventional antibiotics against organisms from skin infections: an in vitro study. J Drugs Dermatol. In press.

Chua EO, Verallo-Rowell VM. 2007. Coconut oil extract 2% monolaurin cream in the treatment of Molluscum contagiosum. A randomized double-blind vehicle-controlled trial. Scientific Poster presentation, World Congress of Dermatology October 1-5 2007, Buenos Aires, Argentina. Makati City, Philipp: VSRC files.

Dillague MK, Syah-Tjundawan BS, Verallo-Rowell VM. 2007. The comparative antibacterial effects of virgin coconut oil and olive oil in atopic dermatitis: a double-blind randomized controlled trial. Makati City, Philipp: VSRC files. For submission.

Dim-Jamora KCC, Verallo-Rowell VM. 2006. A double-blind, randomized controlled trial comparing 2% monolaurin cream and 2% Mupirocin cream in the treatment of superficial bacterial skin solutions: A double blind, randomized controlled clinical trial. J

Philipp Dermatol Soc : 15; 2: 31-36. 2006.

Erna Rafaela L. Abraham, M.D., Vermen M. Verallo-Rowell, M.D. and Benilda Q. Baello, R.M.T. Testing of (monolaruin) Versus Isopropyl Alcohol for Antisepsis of Cutaneous Hand Microbes to Prevent Infection. Phil J Microbiol Infect Dis 2000; 29(3):128-135

Harsono RN, Verallo-Rowel VM. 2004. Comparative analysis on the efficacy and safety of VMV Superskin I and VMV Superskin III versus 2% monolaurin in the treatment of acne. Makati City, Philipp: VMV Skin Research Centre + Clinic (VSRC) Files.

Kusuma F, Yap RA, Verallo-Rowell VM. 2007. A randomized double-blind trial comparing virgin coconut oil vs. mineral oil as an antibacterial and emollient in plaque-type psoriasis patients undergoing phototherapy. Makati City, Philipp: VSRC files. For submission.

Malabanan-Guiyab L, Verallo-Rowell VM. 2007. Determination of lauric acid and lauric monoglyceride serum levels after oral intake of virgin coconut oil: a pilot study. Makati City, Philipp: VSRC. To be submitted.

Martires I, Montinola F, Dizon MV. 2006. The effectivity and safety of virgin coconut oil versus 10% zinc oxide ointment in the treatment irritant contact diaper dermatitis in children. Makati Medical Center Annual Resident’s Research Contest, 3rd Prize. 2006.

Nevin, K.G., Rajamohan, T., “Effect of topical application of virgin coconut oil on skin components and antioxidant status during dermal wound healing in young rats,” Skin Pharmacol. Physiol. June 2010;23(6):290-7

“Nutrition Facts – Coconut Meat, Raw,” Nutrition Data Blog

Pineda-de los Santos J, Verallo-Rowell VM. 2004. A vehicle-controlled trial on the safety and efficacy of 2% monolaurin gel in the treatment of mild to moderate inflammatory facial Acne vulgaris. Makati City, Philipp: VSRC Files.

Preuss HG, Echard B, Enig M, et al. Minimum inhibitory concentrations of herbal essential oils and monolaurin for gram-positive and gramnegative bacteria. Mol Cell Biochem 2005;272:29–34.

Preuss HG, Echard B, Zonosi RR. The potential for developing natural antibiotics: Examining oregano and monolaurin. Original Internist 2005;12:119–124.

Pua JM, Verallo-Rowell VM. 2007. A double blind randomized trial to compare the efficacy and safety of 2% monolaurin shampoo vs. 2% Ketoconazole shampoo in the treatment of Pityriasis versicolor in children, adolescents and middle-aged adults. Makati City, Philipp: VSRC files. For submission.

Realubin-Ubalde MD, Gregorio A, Rayco-Solon MP, Solon JAA, Verallo-Rowell VM. 2007. A randomized, three-year secondary prevention trial of virgin coconut oil supplementation for actinic keratosis. Protocol submitted to NAST 2007. Makati City, Philipp: VSRC files. Awaiting decision.

Singson M, Verallo-Rowell VM. 2007. A double-blind, randomized controlled trial comparing 4% monolaurin ointment and 2% Bactroban in the treatment of superficial bacterial skin infections. Makati City, Philipp: VSRC files. For submission.

Sorra LL, Layson CL, Dizon-Co, Verallo-Rowell VM. 2004. An experimental study comparing the efficacy and safety of Chlorhexidine (Surgihex), used as bathing solution, as antimicrobial agents against skin microbial isolates of newborn. Philipp J Pediat 53: pages.

Tiosudarmin F, Verallo-Rowell VM. 2007. Virgin coconut oil for non-complicated diaper dermatitis: a randomized controlled trial. Makati City, Philipp: VSRC files. For submission.

Toledo-Tan JR, Kusuma F, Verallo-Rowell VM. 2007. A pilot study to determine the effect of oral monolaurin on the severity of atopic dermatitis. Makati City, Philipp: VSRC ongoing study.

Trevithick, J.R., Mitton, K.P., “Uptake of vitamin E succinate by the skin, conversion to free vitamin E, and transport to internal organs,” Biochem. Mol. Biol. Int. March 1999;47(3):509-18

Verallo-Rowell VM. 2005. Rx: Coconuts! (The Perfect Health Nut). Philadephia, PA, USA: Xlibris. pp. 91-109.

Verallo-Rowell VM. 2007. Updates in the treatment of acne in pigmented skin. Oral presentation. Acne symposium, World Congress of Dermatology. Buenos Aires, Argentina. October 2007. Makati City, Philipp: VSRC.

Wiedersberg, S., Leopold, C.S., Guy, R.H., “Effects of various vehicles on skin hydration in vivo,” Skin Pharmacol. Physiol. Jan. 2009; 22 (3):128-30.

 

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