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You are here: Home / Shingles (see also, Herpes & Monolaurin) / More Detail on How it Works

More Detail on How it Works


Background

   Fatty acids and monoglycerides produce their killing/inactivating effects by several mechanisms.  An early postulated mechanism was the perturbing of the plasma membrane lipid bilayer.  The antiviral action attributed to monolaurin is that of fluidizing the lipids and phospholipids in the envelope of the virus, causing the disintegration of the microbial membrane.

More recent studies indicate that one antimicrobial effect in bacteria is related to monolaurin’s interference with signal transduction/toxin formation (Projan et al 1994).  Another antimicrobial effect in viruses is due to lauric acid’s interference with virus assembly and viral maturation (Hornung et al 1994).  The third mode of action may be on the immune system itself (Witcher et al, 1993).

Hierholzer and Kabara (1982) first reported the antiviral activity of the monoglyceride of lauric acid (monolaurin) on viruses that affect humans.  They showed virucidal effects of monolaurin on enveloped RNA and DNA viruses.  This work was done at the Center for Disease Control of the U.S. Public Health Service.

This study was carried out using selected virus prototypes or recognized representative strains of enveloped human viruses.  All these viruses have a lipid membrane.  The presence of a lipid membrane on viruses makes them especially vulnerable to lauric acid and its derivative monolaurin.

These initial findings have been confirmed by many other studies.  Research has shown that enveloped viruses are inactivated by added fatty acids and monoglycerides in both human and bovine milk (Isaacs et al 199 1).  Others (Isaacs et al 1986, 1990, 1991, 1992; Thormar et al 1987) have confirmed Kabara’s original statements concerning the effectiveness of monolaurin.

Effectiveness

Some of the viruses inactivated by these lipids are the measles virus, herpes simplex virus (HSV-1 and -2), herpes family members (HIV, hepatitis C, vesicular, stomatitis virus (VSV), visna virus, and cytomegalovirus (CMV).

Many of the pathogenic organisms reported to be inactivated by these antimicrobial lipids are those know to be responsible for opportunistic infections in HIV -positive individuals.  For example, concurrent infection with cytomegalovirus is recognized as a serious complication for HIV positive individuals (Macallan et al 1993).

Thus, it would appear imperative to investigate the practical aspects and the potential benefit of a nutritional supplement, such as monolaurin, for microbial infected individuals.  Until now few nutritionists in mainstream nutrition community seem to have recognized the added benefit of antimicrobial lipids in the support of infected patients.

These antimicrobial fatty acids and their derivatives are essentially nontoxic to man.  According to the published research, lauric acid is one of the best “inactivating” fatty acids, and its monoglyceride is even more effective than the fatty acid alone (Kabara 1978, Sands et al 1978, Fletcher et al 1985, Kabara 1985).

The Monolaurin Advantage

   (It should be emphasized that lauric acid cannot be taken orally because it is severally irritating.)  

   Monolaurin, on the other hand, a derivative of lauric acid chemically bonded to glycerol to form monolaurin, can be taken orally without any problem!

The lipid-coated (envelope) viruses, bacteria and other microorganisms are dependent on host lipids for their lipid constituents.  The variability of fatty acids in the foods of individuals as well as the variability from de novo synthesis accounts for the variability of fatty acids in their membranes.

Monolaurin does not appear to have an adverse effect on desirable gut bacteria, but rather on only potentially pathogenic microorganisms.  For example, Isaacs et al (1991) reported no inactivation of the common Esherichiacoli or Salmonella enteritidis by monolaurin, but major inactivation of Hemophilus influenza, Staphylococcus epidermis and Group B gram positive streptococcus.

The potentially pathogenic bacteria inactivated by monolaurin include Listeria monocytogenes, Staphylococcus aureus, Streptococcus agalactiae, Groups A, streptococci-gram-positive organisms, and some gram-negative organisms (Vibrio parahaemolyticus and Helicobacter pylori).  Decreased growth of Staphylococcus aureus and decreased production of toxic shock syndrome toxin-l was shown with monolaurin (Holland et al 1994).

Monolaurin was 5000 times more inhibitory against Listeria monocytogenes than ethanol (Oh & Marshall 1993).  In vitro monolaurin rapidly inactivate Helicobacter pylori. Of greater significance there appears to be very little development of resistance of the organism to the bactericidal effects (Petschow et al 1996) of these natural antimicrobials. 

Fortunately, shingles can be defeated with our 3-Step Treatment Program.

References:

Enig, MG. Lauric oils as antimicrobial agents: theory of effect, scientific rationale, and dietary applications as adjunct nutritional support for HIV-infected individuals. in Nutrients and Foods in AIDS (RR Watson, ed) CRC Press, Boca Raton, 1998, pp. 81-97.

Epstein SE, Speir E, Zhou YF, Guetta E, Leon M, Finkel T. The role of infection in restenosis and atherosclerosis: focus on cytomegalovirus. Lancet 19%;348 Supplement 1:513-17.

Hierholzer, J.C. and Kabara, J.J. In Vitro Effects of Monolaurin Compounds on Enveloped RNA and DNA Viruses. J. Of Food Safety 4:1-12 (1982).

Holland KT, Taylor D, Farrell AM. The effect of glycerol monolaurate on growth of, and production of toxic shock syndrome toxin-1 and lipase by, Staphylococcus aureus. Journal of Anti-microbial Chemotherapy 1994;33:41-55.

Homung B, Arntmann E, Sauer G. Lauric acid inhibits the maturation of vesicular storriatitis virus. Journal of General Virology 1994;75:353-361.

What People Are Saying:

I have Fibromyalgia and often can’t sleep at night due to pain. Since taking monolaurin before bed, I sleep deeper and with much less pain than in the past.  The relief is significant and lasts.

Eric T. Inspired Nutrition Monolaurin

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I am so grateful there is a product out there like Monolaurin that could help me get healthy in a safe way. Within a month of using Monolaurin, my energy level tripled, and as a result, I’m a much happier person.  

Anonymous, MA Inspired Nutrition Monolaurin

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I have been battling Chronic Lyme Disease and have been supplementing with Monolaurin. I believe this product has helped me cope with Lyme symptoms with no need to fear any bad side effects. 

Anonymous, PA Inspired Nutrition Monolaurin

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My brother told me how the doctors could not believe how our cousin’s wife recovered, when all of us relatives knew she was dying from battling MRSA. She took your products and was healed from it! I know this to be true because she was able to fly to visit family in the last couple of weeks!... No one in our family would ever think she could have done that as bad as she was before with MRSA. What a miracle!

Carolyn H. Inspired Nutrition Monolaurin

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I am a 59 year-old woman and have had major outbreaks of genital herpes since I was 20. I started Monolaurin about 1½ year ago. The only outbreak I’ve had was when I was feeling so good I forgot to take it. Thank you for this wonderful supplement that has changed my life! 

Anonymous, OR Inspired Nutrition Monolaurin

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My daughter and I start taking Monolaurin when we feel like we are getting a cold or sinus infection. We used to get them quite regularly but now we have not had one in 2 years. 

Anonymous, OH Inspired Nutrition Monolaurin

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Before taking Monolaurin, I would have herpes (simplex 1) outbreaks at least once every month. I took Monolaurin 2x a day for one month and have not had a single outbreak since!

Anonymous Inspired Nutrition Monolaurin

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I’ve been using Monolaurin for about 2 years now for Herpes and have not had one outbreak since taking it.  Every once in a while when I feel I may be close to an outbreak, I increase my dosage for a couple of days and it goes away.

Anonymous, CA Inspired Nutrition Monolaurin

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My wife had MRSA so bad that the Dr. said she was going to die. They could not even come close to killing it. She has had MS for 43 yrs but I didn't want MRSA to kill her. She started taking monolaurin &. Bio fibrin & within 2 weeks she was getting better along with cleaning up her UTI infection. She is alive today because of your product, thank you very much!!!

 

Tom K. Inspired Nutrition Bio Fibrin

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Using the Monolaurin and Bio-Fibrin, I brought my viral load down 2 million with the first Jar.  

Leola A. Inspired Nutrition Bio-Fibrin

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The Monolaurin has been a miracle for helping me with my shingles.  I am symptom-free after taking it for just a short time at three scoops a day. 

Susan F. Inspired Nutrition Monolaurin

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I ordered the C-A-Y Defense cream and this stuff is incredible! It heals everything from my cuts and scratches to my psoriasis, I highly recommend it!

Roberta P. Inspired Nutrition C-A-Y Defense Cream

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I have had Hepatitis C for 25 years and I started taking monolaurin three times a day and in six months my viral load went from 9,990,000 to 468,000, at this rate by my next blood test in six months the virus should be cleared and undetected. 

Anonymous Inspired Nutrition Monolaurin

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After my diagnosis of HIV/AIDS 3 years ago, your products brought me to a degree of health I experienced as an athlete prior to my diagnosis. I am free of HIV through multiple tests and off all pharm. medicines.  

Kirk E. Inspired Nutrition Monolaurin

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Thanks to your protocol I on my way to ridding myself of Hepatitis C. after 20 years! My viral load was 10 million + and after 90 days of monolaurin, 3 scoops per day, it has dropped to under 2 million! 

Richard W. Inspired Nutrition Monolaurin

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I’m a holistic health practitioner with over 30 years of experience. I’ve suffered from chronic fatigue syndrome and slowly worked up to 3 full scoops of Monolaurin a day and can’t believe the results…I haven’t felt this good in YEARS!

Marcie J. Inspired Nutrition Monolaurin

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Nothing ever worked to rid my skin problem like Skin Defense. So I am ordering the 32oz bottle. 

G.L Ramona Inspired Nutrition Skin Defense

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