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You are here: Home / MRSA Information (see also Monolaurin) / Clinical Studies of MRSA

Clinical Studies of MRSA

(There are clinical studies topically related to our research here.  We prefer to base our nutritional products on clinical studies more than testimonies.  Some studies are listed at the end of particular articles. More studies can be found under the general topics of Monolaurin, Lactoferrin, Essential Oils, etc.)

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Antimicrobial Action of Isomeric Fatty Acids on Group A Streptococcus Journal of Medicinal Chemistry 16:1060-1063 (1973)

Equivalence of Lauric Acid and Glycerol Monolaurate as Inhibitors of Signal Transduction in Staphylococcus aureus. Journal of Bacteriology. 2000 May; 182(9): 2668-2671

Glycerol Monolaurate (GML) inhibits the production of beta-lactamase, toxic shock toxin-1, and other staphylococcal exoproteins by interfering with signal transduction. Journal of Bacteriology. 1994 July; 176(14): 4204-4209

Holland KT, Taylor D, Farrell AM. The effect of glycerol monolaurate on growth of, and production of toxic shock syndrome toxin-1 and lipase by, Staphylococcus aureus. Journal of Anti-microbial Chemotherapy 1994;33:41-55.

Kabara. J.J.. Conley. A J.- Swieczkowski. D M. Ismail, I.A . Lie Ken Jie and Gunstone, F D Antimicrobial Action of Isomeric Fatty Acids on Group A Streptococcus J. Med Chem 16:1060-1063 (1973)

Modulation of immune cell proliferation by glycerol monolaurate. Clinical and Diagnostic Laboratory Immunology. 1996 January; 3(1): 10-13

Peterson, M., K. Ault, M. J. Kremer, A. J. Klingelhutz, C. C. Davis, C. A. Squier, and P. M. Schlievert. 2005. Innate immune system is activated by stimulation of vaginal epithelial cells with Staphylococcus aureus and toxic shock syndrome toxin-1. Infect. Immun. 73:2164–2174.

89] Peterson, M. L., and P. M. Schlievert. 2006. Glycerol monolaurate inhibits the effects of gram-positive select agents on eukaryotic cells. Biochemistry 45:2387–2397.

Preuss HG, Echard B, Dadgar A, et al. Effects of essential oils and monolaurin on Staphylococcus aureus: In vitro and in vivo studies. Toxicol Mech Method 2005;15:279–285.

Preuss HG, Echard B, Enig M, et al. Minimum inhibitory concentrations of herbal essential oils and monolaurin for gram-positive and gram-negative bacteria. Mol Cell Biochem 2005;272:29–34.

Projan SJ, Brown-Skrobot S, Schlievert PM. Glycerol monolaurate inhibits the production of B-lactamase, toxic shock syndrome toxin-1 and other staphylococcal exoproteins by interfering with signal transduction. J Bacteriol 1994;176:4204–4209.

Pollack, M., W. G. Weinberg, W. J. Hoskins, W. F. O’Brien, P. B. Iannini, S. E. Anderson, and P. M. Schlievert. 1983. Toxinogenic vaginal infections due to Staphylococcus aureus in menstruating rhesus monkeys without toxicshock syndrome. J. Infect. Dis. 147:963964.

Reduction in Staphylococcus aureus Growth and Exotoxin Production and Levels Due to Glycerol Monolaurate in Tampons. Clin Infect Dis. 2009 Oct 28; 19863450

Ruzin A, Novick RP. Glycerol monolaurate inhibits induction of vancomycin resistance in Enterococcus faecalis. J Bacteriol 1998;180:182–185.

Ruzin A, Novick RP. Equivalence of lauric acid and glycerol monolaurate as inhibitors of signal transduction in Staphylococcus aureus. J Bacteriol 2000;182:2668–2671.

Schlievert, P. M. 1982. Enhancement of host susceptibility to lethal endotoxin shock by staphylococcal pyrogenic exotoxin type C. Infect. Immun. 36:123–128.

Schlievert, P. M., K. N. Shands, B. B. Dan, G. P. Schmid, and R. D. Nishimura. 1981. Identification and characterization of an exotoxin from Staphylococcus aureus associated with toxic-shock syndrome. J. Infect. Dis.143:509–516.

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