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You are here: Home / Lyme Disease Basics / Clinical Studies Lyme Disease and Monolaurin

Clinical Studies Lyme Disease and Monolaurin


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There are clinical studies topically related to our research here.  We prefer to base our nutritional products on clinical studies more than testimonies.  Some studies are listed at the end of particular articles. More can be found under the general topics of Monolaurin, Biofilms, Essential Oils, etc.).  Monolaurin has had tremendous success against Lyme Disease.  It disrupts the skin (envelope) and also disrupts signals within it.

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Barthold, S. W., E. Fikrig, L. K. Bockenstedt, and D. H. Persing. 1995. Circumvention of outer surface protein A immunity by host-adapted Borrelia burgdorferi. Infect. Immun. 63:2255-2261.

Fraser, C. M., S. Casjens, et.al.  1997. Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi. Nature 390:580-586.

Fletcher, R.D., Albers, A.C., Albertson, J.N. Jr. and Kabara, J.J. Effect of Monoglycerides on Mycoplasma pneumoniae Growth. In: The Pharmacological Effect of Lipids 11, Jon J. Kabara, ed. American Oil Chemists’ Society: Champaign, Illinois, pp. 59-63 (1985

Glycerol monolaurate prevents mucosal SIV (simian immunodeficiency virus)transmission. Nature. 2009 April; 458: 1034-1038

Glycerol Monolaurate (GML) inhibits the production of beta-lactamase, toxic shock toxin-1, and other staphylococcal exoproteins by interfering with signal transduction. Journal of Bacteriology. 1994 July; 176(14): 4204-4209

Glycerol Monolaurate (GML) in Virgin Coconut Oil destroys tuberculosis bacteria. Living with Nature by Dr. Abercio V. Rotor, 2009 June.

Gromley James, Tishfield Caren, User’s Guide to Treating Lyme’s Disease, Basic Health Publications, 2006.

Isaacs CE, Thormar H. The role of milk-derived antimicrobial lipids as antiviral and antibacterial agents. In: Mestecky J, et al, eds. Immunology of Milk and the Neonate. New York: Plenum Press, 1991.

Isaacs CE, Kashyap S, Heird WC, et al. Antiviral and antibacterial lipids in human milk and infant formula feeds. Arch Dis Child 1990;65:861–864.

Kabara. J.J, Swieczkowski, D M. Conley. A J and Truant, J P Fatty Acids and Derivatives as Antimicrobial Agents and Chemotherapy 2(l):23-28 (1972)

Kabara. J.J., Vrable, R. and Lie Ken Jie, M.S.F Antimicrobial Lipids: Natural and Synthetic Fatty Acids and Monoglycerides. Lipids 12:753759 (1977)

Kabara, JJ Fatty Acids and Derivatives as Antimicrobial Agents-A Review. In: The Pharmacological Effect of Lipids. Jon J. Kabara, ed Champaign, Illinois: The American Oil Chemists’ Society (1979),pp. 1-14

Kabara. J.J. Antimicrobial Agents Derived From Fatty Acids. J. American Oil Chemists’ Society 61:397-403 (1984)

Kristmundsdóttir, T., Árnadóttir, S.G., Bergsson, G., and Thormar, H. Development and evaluation of microbicidal hydrogels containing monoglycerides as the active ingredient.Journal of Pharmaceutical Science 88, 1011-1015, 1999.

Preuss HG, Echard B, Zonosi RR. The potential for developing natural antibiotics: Examining oregano and monolaurin. Original Internist 2005;12:119–124.

Schlievert, P. M., J. R. Deringer, M. H. Kim, S. J. Projan, and R. P. Novick. 1992. Effect of glycerol monolaurate on bacterial growth and toxin production. Antimicrob. Agents Chemother. 36:626–631.

Wang LL and Johnson EA. Inhibition of Listeria monocytogenes by fatty acids and monoglycerides. Applied and Environmental Microbiology 1992;58:624-629.

Witcher KJ, Novick RP, Schlievert PM. Modulation of immune cell proliferation by glycerol monolaurate. Clinical and Diagnostic Laboratory Immunology 1996;3:10-13.

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