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You are here: Home / Kidney Disease / How Kidney Disease and Scar Tissue Work 

How Kidney Disease and Scar Tissue Work 

The primary function of the kidneys is to rid the body of the waste produced through the breakdown of protein.  This produces the main waste product of urea, which is normally passed out of the body in the urine.   

Azotaemia – If your kidneys malfunction, urea builds up in your body, accumulating in the kidneys, bloodstream and elsewhere and is called azotaemia.   Azotaemia can be mild with no symptoms but, if the waste continues to build up for long enough, your kidney function can begin to fail.

Uraemia – When symptoms of kidney failure become apparent (usually when 80% of function has been lost) the condition is called uraemia.

Acute and Chronic Renal Failure

   Acute renal failure –

This is a sudden, severe failure of the kidneys that usually occurs as a result of another disorder. Most people with acute renal failure recover but kidney function may not return to its previous capacity. Your kidneys should begin to heal within about two to six weeks and improvements will continue for three to 12 months.  This can cause some scar tissue buildup but doesn’t continue once inflammation dies down.

   Chronic renal failure –

This is also called chronic kidney disease, describes the gradual loss of kidney function.  When chronic kidney failure reaches an advanced stage, dangerous levels of fluid, electrolytes and wastes can accumulate in your body.  When this occurs, the kidneys become what is called ‘irreversibly damaged’ (ie: no standard medical answer) and cannot function properly.  Chronic nephritis is a persistent, destructive inflammation of both kidneys that occurs as a result of the body’s production of substances that attack and destroy the kidney cells. Healthy tissue is replaced by useless scar tissue, resulting in reduced kidney function.

   This may be caused by:

• Inflammation of the microscopic filtration blood vessels (glomerulonephritis).
• Diabetes.
• Polycystic kidney disease.
• Drug abuse.
• Infections of the kidney.
• Obstructions such as kidney stones and cancers.

   Three Stages of usual progression of chronic renal failure:

1.  Initially, there is an unnoticeable decrease in kidney function – because the remaining healthy kidney cells compensate for the damaged cells.  At this stage a person may live an active lifestyle for many years and it may be years before any symptoms are noticed.  Chronic kidney damage is often discovered by accident during routine blood or urine tests.

2.  With increased destruction of kidney cells, kidney function continues to decline to about a quarter of its capacity.

3.  The last stage of chronic renal failure results in the build-up of waste matter in the blood when symptoms become apparent (uraemia).

   Chronic kidney disease tends to be irreversible by standard treatments.  If it is widespread, involving both kidneys, total renal failure may occur. It occurs over time and needs to be treated as soon as it is diagnosed, rather than waiting for symptoms which may take years to present themselves.

   Kidney dialysis or a kidney transplant may need to be commenced if these measures are not enough to control the disease. Obviously, attending hospital for dialysis can be uncomfortable, time-consuming and expensive.

Kidney Scar Tissue

      Fibrosis refers to the excessive and persistent formation of scar tissue, which is often responsible for mortality associated with organ failure in a variety of chronic diseases including the kidneys and liver!  There are no standard therapies on the market today that have been shown to arrest or prevent fibrotic disease.

  Tissue remodeling and scarring is part of the normal wound healing process.  However,repeated injury and insult can lead to persistent and excessive scarring and, ultimately, organ failure.

   Recently, scientific discoveries are revealing CTGF’s (connective tissue growth factors) role in fibrosis – especially in the normal process of tissue repair called ETM repair.  EMT promotes healing of tissues with fibrin, among other things, and is shut down once healing has occurred.

   However, the recurring attack and inflammation in chronic diseases, results in elevated levels of CTGF.  The persistent ETM “over repair” leads to too much fibrin production – which builds up into scar tissue in kidney, liver and lung tissue!  Thus, EMT is a final common pathway that underlies all forms of chronic fibrosis.

The Answer!

The process of tissue repair is complex, but it has been known for some time that inflammation can be degenerative if it goes too long and forms scar tissue.  It is now appreciated that permanent scar tissue takes a long time to develop.  However, there is also an increasing acceptance that fibrosis is also dynamic and therefore amenable to reversal!  Thus, targeting a key participant such as CTGF (with our Inflammation Relief Formula) can beneficially influence outcome in repair.

Then, the enzymes we recommend, Biofilm Dissolving Enzymes can then also affect a reversal of fibrosis scar tissue.

Whatever the cause, kidney scarring can be helped by the Inflammation Relief Blend reducing the inflammation cause of scar tissue buildup.

Finally, if there is an infection that is part of the Kidney disease, the Monolaurin can get rid of it.

Together, they make a kidney disease protocol able to change a person’s life!

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